Being a polymer scientist working on advanced materials technologies for biopharmaceutical purification solutions is
as complex – and important– as it sounds.
“My kids know I'm a scientist, but it's hard to explain to them what I do every day,” said Dr. Jonathan
Hester, a research scientist at 3M. “I work on advanced materials that go into filters that are used to purify
lifesaving drugs, including COVID-19 vaccine and therapeutic candidates.”
A job that has never been more important
Complicated as it may seem, during a pandemic, Jonathan’s job has never mattered more.
“COVID-19 has changed the world,” he explains, noting that this might not be the last pandemic the world
sees, “so we have to get better at solving this problem.”
In the 1990s, when 3M scientists started work on a
small biopharmaceutical filtration project, they had no idea their effort would become a part of
today’s fight against COVID-19. That resulting product line – the 3M™ Emphaze™ AEX Hybrid
Purifier – uses a unique filter material that captures impurities while allowing
the necessary drug substances to pass through during the drug manufacturing process. This
technology combines two processes into a single step, which can help researchers obtain their final product
more efficiently and in greater amounts.
“Once you get a large group of people sharing the same vision and idea, and especially if they have super
different skill sets and everybody believes, it's almost like you can create something that you didn't think was
possible.”
Thanks to Jonathan and the efforts of a collaborative team of 3M biochemists, bioprocess engineers, mechanical
designers and other research scientists, 3M is finding rapid solutions. In fact, in addition to helping
in the fight against COVID-19, 3M products are also used globally to
manufacture life-saving medications used to treat conditions such as rheumatoid arthritis,
multiple sclerosis and types of cancer such as lung cancer, lymphoma and myeloma.
“It gives me great optimism to see what we're able to accomplish and what this industry has done. Twenty years
ago, the
kinds of protein-based drugs that are now being used to help people were just lab curiosities that could be
produced in only nanogram quantities; mass producing them on a large scale was unreachable. And so over years and
decades, people have kept working on it, and now we can manufacture them in industrial quantities.”
Impossible is part of the job description
For research scientists at 3M, working to discover the impossible is the job description. But Jonathan only has to
look to his family to find all the motivation he needs.
"One day, my kids will realize I wasn't just trying to help them go out and play again, I was trying to make it safer
for the whole world to get back outside, too."